Alternative name:
Description: Presence of antibodies associated with neuromyelitis optica (Devic’s syndrome) which is debated to be a subtype of multiple sclerosis or a distinct disease.
Indication: Inflammatory and demyelinating diseases of CNS particularly with optic nerve involvement
Interpretation: Reported sentsitivity and specificity of 91% and 100% for NMO. Found in both Caucasian and Japanese patients
Sample: Serum Separator Tube (SST)
Assay details: Indirect immunofluorescence using aquaporin 4 transfected cell line
Restrictions: Referred test: only available to Neurology staff
Reference range: neg/low positive/positive
Assay range notes:
Turnaround time: 28 days
Analysing laboratory: Churchill Hospital Department of Immunology