Alternative name:
Description: Autoantibodies recognising endocrine organs are found alone or with related autoantibodies in a group of complex disorders termed Autoimmune polyendocrinopathy syndromes (APS). The autoantibodies against specific organs correlate with disease affecting those organs. Antibodies include anti-adrenal, thyroid, parathyroid, pancreas (diabetes), gastric parietal cell, ovary or testes (see specific pages). These autoantibodies are found individually or together in autoimmune disorders forming part of two types of polyglandular autoimmune syndromes (PAS). Type I is a triad of Addison’s disease, hypoparathyoidism and chronic mucocutaneous candidiasis: Type II is associated with primary hypothyroidism and/or type 1 diabetes. Autoimmune gastritis can also be associated.For further details see individual tests.
Indication: Autoimmune polyendocrinopathy syndromes (APS, PAS or PGA).
Interpretation: See individual tests.
Sample: Serum Separator Tube (SST)
Assay details: Indirect immunofluorescence using primate tissues
Restrictions: Referred tests
Reference range: Negative/positive
Assay range notes: See individual tests
Turnaround time: 28 days
Analysing laboratory: Sheffield PRU