Clinical Use:
Background: CK-MB is a dimeric enzyme. Three different iso-forms occur in normal circulation: CK-MM (muscle type), CK-BB (brain type) and CK-MB that is primarily associated with the myocardium.

The measurement of CK-MB mass in serum is an important element in the diagnosis of myocardial ischaemia. Increased levels of CK-MB are detectable at 3 – 8 Hours after the onset of cardiac symptoms and may remain raised for several days.

CK-MB may appear raised in other conditions such as rhabdomyloysis or stroke. For this reason, CK-MB is measured in conjunction with Total CK and other cardiac markers such as Troponin T and/or Myoglobin to produce a more clear clinical picture

Reference Ranges: Male: 0 – 5.0 ug/L
Female: 0 – 2.9 ug/L
Associated Diseases:
Patient Preparation:
Specimen Requirements: Sample type:

  • Serum

Sample identification:

  • Three patient identifiers from
    • Name
    • D.O.B.
    • Address
    • N.H.S. number
    • Unit Number

    should match on the specimen and request form. This check may be performed prior to centrifugation by the Central Sort department.

Turnaround Time: 2 hours
Additional Information:
Referred Test: