Clinical use
Detection of Ureaplasma spp.
Background
Ureaplasma can be part of the normal genital flora of adults. It can also be found as a trainset coloniser of neonates. – Ureaplasma spp have been associated with various genitourinary tract infections, complications of pregnancy and neonatal disease, however the precise role of this organism in disease has not been fully defined. It can be identified in samples from asymptomatic individuals, and is unlikely to be detected alone, rather being found mixed with other bacteria. Ureaplasma investigation is a referred test, as specified techniques are required for testing.
Two reference laboratories are used for Ureaplasma investigation. Microbiology at James Cook University Hospital refer the sample to the most appropriate lab.
If Ureaplasma testing is to be requested, please discuss the indication for testing with the Consultant Microbiologist before sending samples to the laboratory.
Specimen requirements
| Testing laboratory | Sample container | Samples accepted |
|---|---|---|
| UKHSA Colindale (PCR and/or culture testing) | White topped sterile container | Respiratory specimens, CSF joint and wound aspirates |
| Micropathology Ltd (PCR testing) | White topped sterile container | Urine, genital swabs For Neonates – NPA, ET secretions |
Minimum volume
200µl
Turnaround time
UKHSA RVPBRU:
- PCR: 5 days
- Culture: up to 42 days
Micropathology Ltd:
- PCR: 2 days
Analysing laboratory
UKHSA Colindale Bacteriology: RVPBRU (Respiratory and vaccine preventable bacteria reference unit), UK Health Security Agency, 61 Colindale Avenue, London, NW9 5EQ
Or
Micropathology Ltd, University of Warwick Science Park, Venture Centre, Sir William Lyons Road, Coventry, CV4 7EZ