|Clinical use:||Tests of urine will show if the individual is excreting too many stone-forming minerals or too few stone-inhibiting substances.|
|Background:||Kidney stones often have no definite, single cause. A number of factors, often in combination, create the conditions in which susceptible people develop kidney stones. Kidney stones form when the components of urine, fluid and various minerals and acids are out of balance. When this happens, urine contains more crystal-forming substances, such as calcium, oxalate and uric acid, than the available fluid can dilute. At the same time, urine may have low concentration of substances that inhibit crystal formation e.g citrate. This creates an environment in which kidney stones are more likely to form. Most kidney stones contain crystals of more than one type.
Types of kidney stones include:
Cystine stones, these stones represent only a small percentage of kidney stones. They form in people with a hereditary disorder that causes the kidneys to excrete excessive amounts of certain amino acids (cystinuria).
|Specimen requirements:||Sample type – 24h urine collection in a plain collection bottle|
|Turnaround time:||2 weeks|
|Referred test:||Referred test|