ACU publications

2026

Right Ventricular Function After Mitral Valve Surgery: Insights From the United Kingdom Mini Mitral Study

2025

Inhibition of fractalkine signalling reduces intramyocardial haemorrhage and left ventricular thrombus in patients with acute myocardial infarction by modulating immunothrombosis (The FRACTAL trial)

Early blood-derived predictors of final infarct size in patients with anterior STEMI and primary PCI

Cardiometabolic Outcomes with Dapagliflozin After Myocardial Infarction by Baseline Ejection Fraction: DAPA-MI

‘Clinical impact of cardiac magnetic resonance imaging in myocardial infarction with non-obstructive coronary arteries: a prospective multicentre cohort study’

‘Surgery versus conservative management for severe pectus excavatum (RESTORE): protocol for a multicentre, randomised, controlled superiority trial’

‘Minimally invasive thoracoscopically-guided right minithoracotomy versus conventional sternotomy for mitral valve repair: a multicentre randomised controlled trial (UK Mini Mitral)’

‘Use of accelerometry to measure the impact of remifentanil on sleep after mitral valve repair surgery’

Long-Term Outcomes of Native Infective Endocarditis After Surgery: A Single-Centre Experience. 

‘Discrepancies and potential impacts of self-reported versus measured height and weight on adult transthoracic echocardiography findings’

‘Development of a minimum checklist to assess the quality of evidence produced using registry data for the evaluation of medical device safety and performance’

‘Socioeconomic deprivation: barriers to guideline implementation for cardiovascular disease’

‘Call to collaborate on data science for older people across Europe: an EuGMS Big Data Special Interest Group position paper’

‘Recommended methodologies for clinical investigations of high-risk medical devices—Conclusions from the European Union CORE–MD Project’

‘Outcome measures for randomised clinical trials and multicentre observational studies of cardiovascular diseases published in major clinical journals: systematic review and evidence mapping’

‘Perceptions of older people regarding drone-delivered defibrillators for out-of-hospital cardiac arrest: a qualitative study’

‘The impact of drone delivery of an automated external defibrillator: a simulation feasibility study’ 

Systematic screening for atrial fibrillation with non-invasive devices: a systematic review and meta-analysis’

2024

‘Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine’

‘Graves-PCD: protocol for a randomised, dose-finding, adaptive trial of the plasma cell-depleting agent daratumumab in severe Graves’ disease’

‘The Barts Surgical Infection Risk tool (B-SIR): external validation and comparison with existing tools to predict surgical site infection after cardiac surgery’

‘Patient-Prosthesis Mismatch Rate When Theoretical Ideal Body Weight Is Taken Into Account’

‘Common cardiac surgical procedures: bypass, valve repair and replacement’

Abstract 4142010: The Evolving Risk of Infective Endocarditis after Transcatheter Aortic Valve Replacement

Mitral valvular surgery outcomes in a centre with a dedicated mitral multi-disciplinary team

Improving generalisability: a reply

7 A multi-centre randomised controlled trial of standard care versus an accelerated care pathway after cardiac surgery (FARSTER-care)

Inequalities in access to and outcomes of cardiac surgery in England: retrospective analysis of Hospital Episode Statistics (2010-2019)

Potassium Supplementation and Prevention of Atrial Fibrillation After Cardiac Surgery: The TIGHT K Randomized Clinical Trial

Rationale and design of the early valve replacement in severe asymptomatic aortic stenosis trial

Antithrombotic therapy after heart valve surgery: contemporary practice in the UK

Feasibility study of rehabilitation for cardiac patients aided by an artificial intelligence web-based programme: a randomised controlled trial (RECAP trial)—a study protocol

Prehabilitation for people undergoing cardiac surgery

Rationale and design of the United Kingdom Heart Failure with Preserved Ejection Fraction Registry

Dapagliflozin in Myocardial Infarction without Diabetes or Heart Failure

Role of Lipoprotein(a) Reduction in Cardiovascular Disease

Preventing Cardiac Damage in Patients Treated for Breast Cancer and Lymphoma: The PROACT Clinical Trial

Invasive Treatment Strategy for Older Patients with Myocardial Infarction 

Definitions of clinical study outcome measures for cardiovascular diseases: the European Unified Registries for Heart Care Evaluation and Randomized Trials

Quality indicators for improved cardiovascular care: learnings from the National Institute for Health and Care Excellence

Standardised and hierarchically classified heart failure and complementary disease monitoring outcome measures: european Unified Registries for heart Care evaluation and randomised trials

Automated external defibrillator location and socioeconomic deprivation in Great Britain

European Society of Cardiology quality indicators update for the care and outcomes of adults with heart failure. The Heart Failure Association of the ESC

Feasibility study of rehabilitation for cardiac patients aided by an artificial intelligence web-based programme: a randomised controlled trial (RECAP trial)—a study protocol

Defining the need for cardiovascular event definitions

Actioning atrial fibrillation identified by ambulance services in England: a qualitative exploration

Embracing the promise of Patient Reported Outcome Measures in cardiology

Cohort profile: the European Unified Registries On Heart Care Evaluation and Randomized Trials (EuroHeart)—acute coronary syndrome and percutaneous coronary intervention  

2023

Automated external defibrillator location and socioeconomic deprivation in Great Britain

Fractalkine Signalling (CX3CL1/CX3CR1 Axis) as an Emerging Target in Coronary Artery Disease

Experiences of patients enrolled and staff involved in the prehabilitation of elective patients undergoing cardiac surgery trial: a nested qualitative study

A randomised controlled trial of prehabilitation in patients undergoing elective cardiac surgery

Minithoracotomy vs Conventional Sternotomy for Mitral Valve Repair; A Randomized Clinical Trial

Activation of telomerase by TA-65 enhances immunity and reduces inflammation post myocardial infarction

Prehabilitation in elective patients undergoing cardiac surgery: a randomised control trial (The PrEPS Trial) – a study protocol

Preventing cardiotoxicity in patients with breast cancer and lymphoma: protocol for a multicentre randomised controlled trial (PROACT)

Sex differences in treatment and outcomes amongst myocardial infarction patients presenting with and without obstructive coronary arteries: a prospective multicentre study

Angiographic and Procedural Characteristics in Frail Older Patients with Non-ST Elevation Acute Coronary Syndrome

Pre-operative and prehabilitation services in UK cardiac surgery centres,

A randomised controlled, feasibility study to establish the acceptability of early outpatient review and early cardiac rehabilitation compared to standard practice after cardiac surgery and viability of a future large-scale trial (FARSTER). Pilot Feasibility Study

Efficacy and safety of carbon dioxide insufflation for brain protection for patients undergoing planned left-sided open heart valve surgery: protocol for a multicentre, placebo-controlled, blinded, randomised controlled trial (the CO2 Study)

Minimal Access Aortic Valve Surgery

Impact of gender, ethnicity and social deprivation on access to surgical or transcatheter aortic valve replacement in aortic stenosis: a retrospective database study in England

Improving generalisability: a reply

Grant SW, Chung JCY, Ouzounian M. Can the Media Predict Aortic Events? Thorac Surg. 2022 Nov;114(5):1654-1655. doi: 10.1016/j.athoracsur.2022.04.006. Epub 2022 Apr 22. PMID: 35461786

Grant SW, Ouzounian M, Chung JCY. External Aortic Wrapping for Type A Dissection: SEWing but Not as We Know It. Ann Thorac Surg. 2023 Jan;115(1):60-61. doi: 10.1016/j.athoracsur.2022.07.008. Epub 2022 Jul 19. PMID: 35863390

Grant SW, Macnab A, Dimarakis I. Bilateral Pulmonary Embolism and Impending Paradoxical Embolism After COVID-19 Vaccination. J Cardiothorac Vasc Anesth. 2023 Sep;37(9):1837. doi: 10.1053/j.jvca.2023.05.019. Epub 2023 May 11. PMID: 37301701

Argus L, Taylor M, Ouzounian M, Venkateswaran R, Grant SW. Risk Prediction Models for Long-Term Survival after Cardiac Surgery: A Systematic Review. Thorac Cardiovasc Surg. 2023 Feb 7. doi: 10.1055/s-0043-1760747. Online ahead of print. PMID: 36750201

Moon RJ, Taylor R, Miklavc P, Mehdi SB, Grant SW, Bittar MN. Wedge resection versus lobectomy in T1 lung cancer patients: a propensity matched analysis. J Cardiothorac Surg. 2023 Aug 24;18(1):252. doi: 10.1186/s13019-023-02303-4. PMID: 37620956

Sammut-Powell C, Williams R, Sperrin M, Thomas O, Peek N, Grant SW. Healthcare utilisation in patients with long-term conditions during the COVID-19 pandemic: a population-based observational study of all patients across Greater Manchester, UK. BMJ Open. 2023 Jul 7;13(7):e066873. doi: 10.1136/bmjopen-2022-066873. PMID: 37419643

King J, Taylor M, Booton R, Crosbie P, Shah D, Evison M, Ng C, Rammohan K, Shah R, Shackcloth M, Grant SW, Sinnott N. Safety of curative-intent lung cancer surgery in older patients (octogenarians): A contemporary multicentre cohort study. J Geriatr Oncol. 2023 Oct 7;14(8):101635. doi: 10.1016/j.jgo.2023.101635. Online ahead of print. PMID: 37812970

2022

Taylor M, Templeton R, Granato F, Eadington T, Shah R, Grant SW. The Impact of Initial Postoperative Destination on Unplanned Critical Care Admissions After Lung Resection.J Cardiothorac Vasc Anesth. 2022 Aug;36(8 Pt A):2393-2399. PMID: 35144870

Brunswicker A, Taylor M, Grant SW, Abah U, Smith M, Shackcloth M, Granato F, Shah R, Rammohan K; North West Thoracic Surgery Collaborative (NWTSC)†. Pneumonectomy for primary lung cancer: contemporary outcomes, risk factors and model validation. Interact Cardiovasc Thorac Surg. 2022 Jun 1;34(6):1054-1061. PMID: 34871415

Preventing cardiotoxicity in patients with breast cancer and lymphoma: protocol for a multicentre randomised controlled trial (PROACT)

Which antithrombotic strategy provides the best outcomes after mitral valve repair in patients who remain in sinus rhythm?

Getting the best from the Heart Team: guidance for cardiac multidisciplinary meetings

Determinants of outcomes in 4203 patients following surgery for type A acute aortic dissection. An analysis of the UK National Adult Cardiac Surgical Audit

Evidence gaps pertaining to high-risk medications – Commentary on anticoagulation in new onset postoperative atrial fibrillation

Triiodothyronine (T3), inflammation and mortality risk in patients with acute myocardial infarction

Right ventricular mechanics in anthracycline chemotherapy: insights into the PROACT PLUS study

Non-anemic iron deficiency predicts prolonged hospitalisation following surgical aortic valve replacement: a single-centre retrospective study

2021

Impact of prehabilitation on objectively measured physical activity levels in elective surgery patients: a systematic review