|Clinical Use:||Differential diagnosis of spontaneous hypoglycaemia.|
|Background:||The measurement of both insulin and C-Peptide is advisable in these investigations since in some cases of insulinoma, insulin levels may be low or marginally inappropriate whereas C-Peptide is almost always raised. Further tests, such as those for ketones, proinsulin, sulphonylureas, growth hormone and the insulin-like growth factors may also be required to complete the diagnostic process.|
|Reference Ranges:||Adult (Fasting): 1.6 – 10.9 mU/L
An interpretation of the result(s) will be provided where sufficient information accompanies the request. The level of Insulin may also give info on possibility of insulin resistance.
|Patient Preparation:||Hypoglycaemia, spontaneous or whilst fasting, must first be established, by regular monitoring of blood glucose levels.
Blood collected in a plain vacutainer or syringe, when the blood glucose concentration (confirmed by laboratory analysis) is less than 2.2 mmol/L (or less than 2.5 mmol/L in patients over 60 years), should be used for the tests.
|Specimen Requirements:||A serum (SST) sample is required for this assay|
|Turnaround Time:||1 week|
|Additional Information:||For samples that are required to be sent frozen there is a courier service that goes to Newcastle every Wednesday.
N.B. Record the blood glucose concentration on the request form.
|Referred Test:||Referred test|