The autoantibody screen is used to detect autoantibodies characteristic of a wide range of autoimmune diseases, Autoantibodies recognising antigens in liver, kidney or stomach are detected. A test for rheumatoid factor is also carried out. The autoantibody screen detects anti-nuclear antibodies; gastric parietal cell antibodies, mitochondrial antibodies, liver-kidney microsomal and smooth muscle antibodies. A number of other autoantibodies of varying diagnostic value are also detected e.g anti-reticulin. Refer to pages defining individual autoantibodies for more information.
Initial investigation of autoimmune liver, stomach or connective tissue diseases.
See individual tests
Serum Separator Tube (SST)
Indirect immunfluorescence mouse tissue (liver kidney stomach)
Assay range notes
Positive samples Titre 1:80 – >1:640
3 – 5 days
Immunology The James Cook University Hospital