Trough or 2-4 hours post dose (consistent)
Theophylline is a drug used for treating asthma by relaxing bronchial smooth muscle and lessening the chance of bronchospasm. Theophylline can also be administered to decrease chances of apnoea in premature babies. The drug is rapidly, consistently and completely absorbed and transformed by the liver into relatively inactive metabolites that are excreted in the urine. As the rate of hepatic biotransformation is dependent on age, diet, illness and the symptoms of toxicity unreliable, then determination of the serum levels is important as part of a TDM programme for the individual. Theophylline measurements are used in the diagnosis and treatment of theophylline overdose and in monitoring its levels in patients to ensure appropriate therapy.
Therapeutic Range: 10 – 20 mg/L
- Serum and Plasma (Lithium Heparin)
- Three patient identifiers from
- N.H.S. number
- Unit Number